Conference Program

An overview of the conference schedule

CHOOSE WHICH DAY TO VIEW:

Tuesday, May 24, 2016

*NOTE: All sessions are in the Van Horne Ballroom AB  unless otherwise noted

4:00 PM
Registration Open
Van Horne Foyer

5:00 PM - 6:00 PM
Welcome Reception

6:00 PM - 6:15 PM
Conference Opening
VIP Greetings

6:15 PM - 7:30 PM
Keynote Address: Potential for Brain Health Promotion and Dementia Prevention
Martin Prince, King's College London

7:30 PM
Dinner on own/Free evening

Wednesday, May 25, 2016

*NOTE: All sessions are in the Van Horne Ballroom AB  unless otherwise noted

7:30 AM - 8:25 AM
Breakfast

8:25 AM - 11:30 AM
Session #1: Brain and Cognitive Resilience in Aging: Trajectories, Biomarkers, Risk and Protection
Session Chair: Roger A. Dixon, University of Alberta and Richard Camicioli, University of Alberta

In a recent statement, the US National Institutes of Health noted that the long-term etiology of Alzheimer’s disease is more complex, dynamic, and interactive than previously understood.  In this session the invited speakers will address timely issues such as: (1) identifyingthe multiple trajectories and full range ofclassifiable outcomes of brain and cognitive aging, (2) examining multi-modal biomarkers (ranging from leading signals of neuropathology or resilience to pivotal risk and protective factors) that independently or interactively modify these trajectories, and (3) developing early risk reduction, protection enhancing, and precision strategies for promoting healthier brain aging, delaying impairment, and preventing dementia.

Modifiers of Trajectories and Outcomes in Brain and Cognitive Aging
Roger A. Dixon, University of Alberta and the Canadian Consortium on Neurodegeneration in Aging (CCNA)

Population Health Approaches to Cognitive Health Promotion and Dementia Risk Reduction
Kaarin J. Anstey, Australian National University

Strategies for Promotion of Cognitive Resilience
Kristine Yaffe, University of California San Francisco

Refreshment Break

The Super Aging Study:  Identifying neurobiologic and psychosocial features associated with unusually high memory performance over age 80
Emily J. Rogalski, Northwestern University

Abstract Presentation: Testing the reserve hypothesis with multi-state Markov models in the Nun Study: Are higher levels of reserve associated with shorter survival after diagnosis of dementia? (36)
Suzanne L. Tyas, University of Waterloo

Abstract Presentation: Investigating Age-Related Changes in Functional Connectivity of the Human Brain with Age (68)
Peter Seres, University of Alberta

 

 

8:30 AM



9:00 AM
 

9:30 AM
 

10:00 AM

10:30 AM
 


11:00 AM

 

11:15 AM
 


11:30 AM - 1:30 PM
Lunch

Poster Viewing
Van Horne C

1:30 PM - 2:15
Invited Lecture: 13 Things You Will Be Able to Do with the CCNA  
Howard Chertkow, McGill University and the Canadian Consortium on Neurodegeneration in Aging (CCNA)

2:15 PM - 2:30 PM
Nutrition Break

2:30 PM - 5:30 PM
Session #2: Vascular Contributions to Cognitive Impairment and Dementia
Session Chair: Eric Smith, University of Calgary

Vascular dementia is the second most common cause of dementia, and potentially the most preventable and treatable. In this session invited speakers will discuss the neuropathology of vascular cognitive impairment, neuroimaging markers of cerebrovascular pathology and blood vessel function, cerebral amyloid angiopathy and its association with cognitive impairment, and paradigms for diagnosis and treatment of early stage patients with vascular mild cognitive impairment to prevent progression to dementia.

Pathologic Insights on the Relationship between Cerebrovascular Disease, Alzheimer’s Disease and Dementia
Julie A. Schneider, Rush University
VIEW PRESENTATION

Innovative Neuroimaging Markers of VCI
Richard Frayne, University of Calgary
VIEW PRESENTATION

Missing Links: Cerebral Amyloid Angiopathy and Cognitive Impairment
Steven Greenberg, Massachusetts General Hospital

Refreshment Break

Vascular Mild Cognitive Impairment as a Target Population for Prevention of Dementia
Eric Smith, University of Calgary and the Canadian Consortium on Neurodegeneration in Aging (CCNA)

Abstract Presentation: Structural and Functional Changes in Cerebral Amyloid Angiopathy (60)
Randall B. Stafford, University of Calgary

Abstract Presentation: Silent Lesions need to be Listened to: Lacunes and White Matter Hyperintesities Attenuate Post-Stroke Outcome (38)
Angela Auriat, University of British Columbia

2:30 PM
 


3:00 PM
 


3:30 PM


4:00 PM

4:30 PM


5:00 PM
 

5:15 PM

 

5:30 PM - 6:30 PM
Poster Viewing
Van Horne C

6:30 PM -
Free Evening

Thursday, May 26, 2016

*NOTE: All sessions are in the Van Horne Ballroom AB unless otherwise noted 

7:30 AM - 8:25 AM
Breakfast

8:25 AM - 11:30 AM
Session #3: Risk Factors and Novel Diagnostics
Session Chair: Jack Jhamandas, University of Alberta

Finding incisive risk factors and diagnostics for Alzheimer’s disease presents a striking challenge; this situation is compounded in a practical way by disease heterogeneity and by contrasting views as to which elements might comprise the pivotal events in pathogenesis.  In this session the invited speakers will discuss the clinical presentation of dementia (including cohorts of rapid-onset disease), novel chemical markers of neuronal damage and protein misfolding, novel therapeutic approaches, perturbations in unexpected neuroanatomical pathways that may presage the advent of MCI or AD and new insights that may emerge from the application of prion biology principles.

Emerging Prion Paradigm of Alzheimer Disease Diversity: Implications for Diagnostic and Therapeutic Strategies
Jiri G. Safar, Case Western Reserve University
VIEW PRESENTATION

Presentation sponsored by the Alberta Prion Research Institute

Alpha2 Macroglobulin and Preclinical Alzheimer's Disease: A Marker of Neuronal Injury through the RCAN1 Pathway
Madhav Thambisetty, National Institutes of Health
VIEW PRESENTATION

Using Fluorescence Spectroscopy for Detection of Alzheimer's
Peter Stys, University of Calgary and the Canadian Consortium on Neurodegeneration in Aging (CCNA)

Refreshment Break

The Amylin Receptor: A Target for Novel Therapeutics in Alzheimer’s Disease
Jack Jhamandas, University of Alberta
VIEW PRESENTATION

Abstract Presentation: Measures of Central Presbycusis in People with Mild Cognitive Impairment and Dementia: Preliminary Outcomes of a Collaboration between Geriatric Medicine and Audiology in SW Alberta (27)
Penny Gosselin, Alberta Health Services

Abstract Presentation: An Expanding Role for Prion Protein in Alzheimer Disease (33)
W. Ted Allison, University of Alberta

8:30 AM
 

 


9:00 AM
 


9:30 AM
 

10:00 AM

10:30 AM
 


11:00 AM

 

11:15 AM
 

11:30 AM - 1:30 PM
Lunch

Poster Viewing
Van Horne C

11:30am-1:25pm               CCNA Luncheon Meeting - Open to All

1:25 PM - 4:30 PM
Session #4: Exercise and Cognitive Interventions for Healthy Brain Aging and Prevention of Dementia
Session Chair: Marc Poulin, University of Calgary and the Canadian Consortium on Neurodegeneration in Aging (CCNA)

With a global dementia epidemic on our doorsteps, this symposium will address the important and emerging role of lifestyle interventions such physical activity, exercise and cognitive activity for brain health with aging and the potential impact of these interventions for the prevention and/or delay of Alzheimer disease and related dementias. The speakers in this session will discuss some of the latest findings in the field, including clinical and translational physiology studies, and the application of recent developments (i.e., neuroimaging, biomarkers, modeling in human and animal research), which are helping to advance our knowledge of the role of physical activity and cognitive interventions for healthy brain aging and for the prevention of dementia. The session will conclude with a panel discussion on the role of exercise and cognitive activity in delaying and/or preventing Alzheimer disease and dementia.

Contributions of Cognitive and Physical Activity to Cognitive Function in Aging
Gail Eskes, Dalhousie University

Practice Effects Detection in Repeated Cognitive Assessments: Conceptual Perspectives and Methodological Considerations
Tolulope Sajobi, University of Calgary

Refreshment Break

Novel Approaches to Understand the Protective Effects of Physical Activity on the Aging Brain
Claire Sexton, University of Oxford

Investigating the Relationships Between Physical Activity and Fitness with Brain Health in Older Adults
Michelle Voss, University of Iowa

Panel Discussion and Q&A

1:30 PM


2:00 PM
 

2:30 PM

3:00 PM
 

3:30 PM


4:00 PM

4:30 PM - 6:30 PM
Free Time

6:30 PM - 9:30 PM
Offsite Dinner- Mountview BBQ
Google Map
**Bus transportation will be provided: buses will leave the Banff Springs at 6:15pm and 6:45pm, with return trips every 30 minutes starting at 9:00pm.

Friday, May 27, 2016

*NOTE: All sessions are in the Van Horne Ballroom AB unless otherwise noted

7:30 AM - 8:25 AM
Breakfast

8:25 AM - 11:30 AM
Session #5: Applied Research in Dementia
Session Co- Chairs: Jayna Holroyd-Leduc, University of Calgary and Sharon Straus, University of Toronto

With the aging world population, the prevalence of dementia is expected to increase. Dementia has a significant impact on individuals and caregivers across the world. This session will focus on applied research targeted on the translation of evidence into practice. In this session, invited speakers will present an array of implementation research initiatives that cross the disease continuum. 

8:30 AM
 


8:50 AM
 

9:20 AM


9:50 AM

10:20 AM
 


10:50 AM



11:15 AM
 

Challenges in Knowledge Translation
Sharon Straus, University of Toronto
VIEW PRESENTATION

Applied Research in Dementia Care in Long Term Care
Dallas Seitz, Queen's University and the Canadian Consortium on Neurodegeneration in Aging (CCNA)

Applied Research in Residential Care - Is Transformative Change Possible?
Greta Cummings, University of Alberta

Refreshment Break

Advanced Dementia: Clinical Course, Complications, and Decision-Making
Susan L. Mitchell, Harvard University
VIEW PRESENTATION

Integrating Dementia-friendly Design and Assistive Technologies to Support Persons with Dementia
David Hogan, University of Calgary and the Canadian Consortium on Neurodegeneration in Aging (CCNA)
VIEW PRESENTATION

Abstract Presentation: Guideline Recommendations for Depression and Anxiety in those with Dementia or Parkinson’s Disease: A Systematic Review (81)
Zahra Goodarzi, University of Calgary and Alberta Health Services

11:30 AM - 1:25 PM
Lunch     

Poster Viewing
Van Horne C                                                            

1:25 PM - 2:15 PM
Keynote Address: Changing Views of the Contribution of the Hippocampus to Memory and to Other Cognitive Functions
Morris Moscovitch, University of Toronto
VIEW PRESENTATION

2:15 PM - 3:30 PM
Closing Panel: Promoting Healthy Brain Aging and Preventing Dementia: Big Ideas and Future Directions
Session Chair: Robert Sutherland, University of Lethbridge

Panelists: 
Kaarin Anstey, Australian National University
David Hogan, University of Calgary
Morris Moscovitch, University of Toronto
Michele Mulder, Alzheimer Society of Alberta and the Northwest Territories
Peter Stys, University of Calgary
 

3:30 PM
Conference Closing